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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
11.52
Human Site:
S166
Identified Species:
18.1
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
S166
A
N
P
H
A
E
I
S
T
K
V
P
A
S
K
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
S166
A
N
P
H
A
E
I
S
T
K
V
P
A
S
K
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
S166
A
H
P
R
A
E
I
S
T
K
V
P
P
S
K
Dog
Lupus familis
XP_536242
380
42964
S167
S
P
P
R
A
E
L
S
T
K
V
L
A
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
H158
P
S
H
T
A
K
P
H
A
E
M
P
I
T
K
Rat
Rattus norvegicus
Q6AYK5
386
43662
P161
A
K
P
N
T
E
V
P
T
K
V
P
S
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
A164
K
Q
P
S
S
Q
V
A
N
K
V
A
S
T
P
Chicken
Gallus gallus
XP_420792
364
42082
K179
E
N
G
V
T
D
G
K
T
E
Q
K
K
N
K
Frog
Xenopus laevis
NP_001086609
360
41600
R162
E
N
S
V
A
E
D
R
P
E
P
P
P
E
A
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
R159
T
T
E
N
C
E
S
R
T
D
L
K
N
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
P133
V
G
N
C
M
R
M
P
R
N
Q
A
T
Q
V
Honey Bee
Apis mellifera
XP_623803
246
28455
E98
E
T
N
L
S
K
T
E
R
N
F
L
N
L
L
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
I105
S
V
A
G
F
A
N
I
P
R
K
E
A
K
F
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
D174
V
S
P
N
S
V
P
D
G
G
V
Q
E
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
100
80
53.3
N.A.
20
53.3
N.A.
20
20
26.6
13.3
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
100
86.6
66.6
N.A.
53.3
80
N.A.
60
40
33.3
26.6
N.A.
6.6
13.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
7
0
40
7
0
7
7
0
0
14
27
0
7
% A
% Cys:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
7
0
7
0
0
0
0
0
% D
% Glu:
20
0
7
0
0
47
0
7
0
20
0
7
7
7
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
7
7
7
0
0
7
0
7
7
0
0
0
7
7
% G
% His:
0
7
7
14
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
20
7
0
0
0
0
7
0
0
% I
% Lys:
7
7
0
0
0
14
0
7
0
40
7
14
7
14
40
% K
% Leu:
0
0
0
7
0
0
7
0
0
0
7
14
0
7
7
% L
% Met:
0
0
0
0
7
0
7
0
0
0
7
0
0
0
0
% M
% Asn:
0
27
14
20
0
0
7
0
7
14
0
0
14
7
0
% N
% Pro:
7
7
47
0
0
0
14
14
14
0
7
40
14
0
7
% P
% Gln:
0
7
0
0
0
7
0
0
0
0
14
7
0
7
0
% Q
% Arg:
0
0
0
14
0
7
0
14
14
7
0
0
0
0
0
% R
% Ser:
14
14
7
7
20
0
7
27
0
0
0
0
14
20
0
% S
% Thr:
7
14
0
7
14
0
7
0
47
0
0
0
7
20
7
% T
% Val:
14
7
0
14
0
7
14
0
0
0
47
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _